CSF1 Pre-design Chimera RNAi
产品名称： CSF1 Pre-design Chimera RNAi
英文名称： CSF1 Pre-design Chimera RNAi
产品编号： H00001435-R04
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
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- Specification
- Product Description:
- Homo sapiens colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_172212
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 1435
- Gene Name:
- CSF1
- Gene Alias:
- MCSF,MGC31930
- Gene Description:
- colony stimulating factor 1 (macrophage)
- Omim ID:
- 120420
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000013362,OTTHUMP00000013363,OTTHUMP00000013364,colony stimulating factor 1,macrophage colony stimulating factor
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Chorioamnionitis
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Inflammation
- Kidney Failure, Chronic
- Neoplasms
- Obstetric Labor, Premature
- Osteitis Deformans
- Ovarian Neoplasms
- Periodontitis
- Pre-Eclampsia
- Premature Birth