CYBA Pre-design Chimera RNAi
产品名称： CYBA Pre-design Chimera RNAi
英文名称： CYBA Pre-design Chimera RNAi
产品编号： H00001535-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens cytochrome b-245, alpha polypeptide (CYBA), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000101
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 1535
- Gene Name:
- CYBA
- Gene Alias:
- p22-PHOX
- Gene Description:
- cytochrome b-245, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq
- Other Designations:
- cytochrome b light chain,cytochrome b(558) alpha-subunit,cytochrome b, alpha polypeptide,flavocytochrome b-558 alpha polypeptide
- Gene Pathway
- Related Disease
- Acute Disease
- Aggressive Periodontitis
- Agranulocytosis
- Albuminuria
- Angina Pectoris
- Angina Pectoris, Variant
- Arteriosclerosis
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Birth Weight
- Brain Infarction
- Brain Ischemia
- Bronchiolitis, Viral
- Candidiasis
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cerebral Infarction