This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. *   http://www.creative-diagnostics.com/Anti-ESM1-PAb-188532-147.htm